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INTRODUCTION

(Each film coated tablets contains: Calcitriol 0.25 mcg + Calcium Carbonate 1250 mg + Elemental zinc 7.5 mg.)

  • Calcium carbonate is a chemical compound. It is commonly used medicinally as a calcium supplement or as an antacid, but excessive consumption can be hazardous.

    Calcium in the body of an adult is about 1200 gms, 99% of this in bones and teeth and rest is in the whole body. Absorption takes place in the jejunum and partly ileum. Found in milk and milk products, vegetables etc. Normally serum Ca level is 10 mg/ml. Serum calcium is regulated by parathyroid hormone. Helps in formation of teeth and bones, in coagulation of blood, in neuro-mascular transmission, regulation of membrane permeability and normal enzymetic activity. Calcium is used in osteoporosis, steroid therapy, rickets, antacid etc. Daily requirement varies from 300 to 1200 mg in variety of patients.

    Zinc Zinc is an essential mineral. In children it causes growth retardation, delayed sexual maturation, infection susceptibility, and diarrhea. Zinc stimulates the activity of about 200 enzymes, maintain healthy immune system, maintains memory, prevents premature delivery, helps AIDS patients to increase immunity, has anti-inflammatory benefits, needed for DNA synthesis , helps normal growth and development, helps sperm production and ovulation, helps in digestion of food, prevents hair loss and Alopecia, provides healthy nails, strengthen bone, helps to fight infection, helps in controlling diabetes, helps acne and wound healing, is vital in protein stnthesis, helps in carrying cabon-di-oxide from the cells. Zinc requirements Infants- 0 - 6 months: 2 milligrams per day (mg/day), 7 - 12 months: 3 mg/day /, Children: 1 - 3 years: 3 mg/day, 4 - 8 years: 5 mg/day, 9 - 13 years: 8 mg/day /Adolescents and Adults - Males age 14 and over: 11 mg/day, Females age 14 to 18 years: 9 mg/day, Females age 19 and over: 8 mg/day.

    Calcitrol increases the level of calcium (Ca2+) in the blood by increasing the uptake of calcium from the gut into the blood, and increasing the release of calcium into the blood from bone.

  • INDICATIONS

    Osteoporosis Osteoporosis is a disease of bones that leads to an increased risk of fracture. In osteoporosis, the bone mineral density (BMD-Avg 2.5) is reduced, bone micro architecture deteriorates, and the amount and variety of proteins in bone are altered.

    Osteoarthritis is a type of joint disease that results from breakdown of joint cartilage and underlying bone. The most common symptoms are joint pain and stiffness. Initially, symptoms may occur only following exercise, but over time may become constant.

    Osteodystrophy is a general term for a dystrophic growth of the bone. It is defective bone development that is usually attributable to renal disease or to disturbances in calcium and phosphorus metabolism. One form is renal osteodystrophy.

    Calcium Deficiency cause for deficiency of calcium, a vital mineral. Your body uses it to stabilize blood pressure and build strong bones and teeth. When you don't get enough calcium, you increase your risk of developing diseases like osteoporosis, osteopenia, and calcium deficiency disease (hypocalcemia).

  • NOTE

    Trochanter is a broad, flat process on the femur, at the upper end of its lateral surface (greater trochanter), or a short conical process onthe posterior border of the base of its neck (lesser trochanter).

    Rheumatoid arthritis is a chronic systemic disease of the joints, usually marked by inflammatory changes in the synovial membrane and articular structure and associated with pain, stiffness or limitations of motion.

    Preeclampsia is a toxemia of late pregnancy, characterized by hypertension , proteinuria and oedema.

    Cytokines are a broad and loose category of small proteins that are important in cell signaling

    Osteopenia is a condition in which bone mineral density is lower than normal.

  • DOSE

    Once daily one tablet or as directed by the doctor.

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