EACH TABLET CONTAINS: SODIUM FEREDETATE B.P. 231MG. (EQV. TO 33MG. OF ELEMENTAL IRON) FOLIC ACID I.P. 1.5MG. VITAMIN B12 I.P. 15MCG. ZINC AS
ZINC GLUCONATE U.S.P 7.5MG. EXCIPIENTS Q.S.
EACH 5 ML CONTAINS: SODIUM FEREDETATE B.P. 231MG. (EQV. TO 33MG. OF ELEMENTAL IRON) FOLIC ACID I.P. 1.5MG. VITAMIN B12 I.P. 15MCG. ZINC AS
ZINC GLUCONATE U.S.P 7.5MG. FLAVOURED SYRUPY BASE Q.S.
Sodium feredetate feredetate which is a new generation haematinic and is a chelate form of iron. It does not dissociate
in the stomach and thus there is minimal gastric disturbances whether it is Diarrohoea, Constipation, Nausea or Vomiting which
is very commonly associated with any conventional iron. The relative bioavailability of sodium feredetate is 2.5 to 10 times
more, therefore sodium feredetate produces faster rise in haemoglobin as compared to conventional iron and carbonyl iron.
Clofiron tablet provides 231 mg of sodium feredetate equivalent to 33mg of elemental iron.
Vitamin B12 Cyanocobalamin) is a water soluble B vitamin. The mechanism of action is straightforward: the hydroxycobalamin
hydroxide ligand is displaced by the toxic cyanide ion, and the resulting harmless B12 complex is excreted in urine.B12 is also
known as cobalamin because it contains cobalt. B12 is only produced by bacteria. So it is only found in food products of animal
origin and in some fermented vegetable products. B12 works closely with another B vitamin, Folic acid in reactions involved with
DNA synthesis, blood cell formation, nervous sytem formation and heart health.
Folic acid is essential for normal erythropoiesis process by exogenous administration. Folic acid is vital for the
biosynthesis of purines and thymidylate of nucleic acids. Folic acid is rapidly absorbed in the proximal portion of the small
intestine. After oral administration, the Cmax can be achieved within one hour. Folic acid is well-distributed in all over the
body tissues and stored in hepatic tissues. Folic acid is metabolized in liver into dihydrofolate and tetrahydrofolate forms.
About 90% of the administered dose is excreted via the urine.
Zinc Zinc is an essential mineral. In children it causes growth retardation, delayed sexual maturation, infection
susceptibility, and diarrhea. Zinc stimulates the activity of about 200 enzymes, maintain healthy immune system, maintains memory,
prevents premature delivery, helps AIDS patients to increase immunity, has anti-inflammatory benefits , needed for DNA synthesis,
helps normal growth and development, helps sperm production and ovulation, helps in digestion of food, prevents hair loss and
Alopecia, provides healthy nails, strengthen bone, helps to fight infection, helps in controlling diabetes, helps acne and wound
healing, is vital in protein stnthesis, helps in carrying cabon-di-oxide from the cells. Zinc requirements Infants- 0 - 6
months: 2 milligrams per day (mg/day), 7 - 12 months: 3 mg/day /, Children: 1 - 3 years: 3 mg/day, 4 - 8 years: 5 mg/day,
9 - 13 years: 8 mg/day /Adolescents and Adults - Males age 14 and over: 11 mg/day, Females age 14 to 18 years: 9 mg/day, Females
age 19 and over: 8 mg/day.
INDICATIONS
Menorrhagia is an abnormally heavy and prolonged menstrual period at regular intervals. Menorrhagia can be caused
by abnormal blood clotting, disruption of normal hormonal regulation of periods, or disorders of the endometrial lining
of the uterus. Depending upon the cause, it may be associated with abnormally painful periods (Dysmenorrhea).
Anaemia is a decrease in number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the
blood. Because hemoglobin (found inside RBCs) normally carries oxygen from the lungs to the tissues, anemia leads to
hypoxia (lack of oxygen) in organs. Anemia can be classified based on the morphology of RBCs. The three main classes
include excessive blood loss (acutely such as a hemorrhage or chronically through low-volume loss), excessive blood cell
destruction (hemolysis) or deficient red blood cell production (ineffective hematopoiesis).
NOTE
Iron chelate, , also known as chelated iron, is a soluble complex of iron, sodium and a chelating agent such as
ethylenediaminetetraacetate (EDTA), EDDHA, or others, used to make the iron soluble in water.
Carbonyl iron is a highly pure (97.5% for grade S, 99.5+% for grade R) iron, prepared by chemical decomposition of
purified iron pentacarbonyl.
Hemoglobin or Hb, is the iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates
as well as the tissues of some invertebrates. Hemoglobin in the blood carries oxygen from the respiratory organs (lungs
or gills) to the rest of the body (i.e. the tissues). For men, 13.5 to 17.5 grams per deciliter and for women, 12.0 to
15.5 grams per deciliter is the normal Hb level.
Serum Ferritin is a universal intracellular protein that stores iron and releases it in a controlled fashion.
DOSE
Once daily one tablet or 5-10 ml or as directed by the doctor.
INTRODUCTION
EACH TABLET CONTAINS: SODIUM FEREDETATE B.P. 231MG. (EQV. TO 33MG. OF ELEMENTAL IRON) FOLIC ACID I.P. 1.5MG. VITAMIN B12 I.P. 15MCG. ZINC AS ZINC GLUCONATE U.S.P 7.5MG. EXCIPIENTS Q.S.
EACH 5 ML CONTAINS: SODIUM FEREDETATE B.P. 231MG. (EQV. TO 33MG. OF ELEMENTAL IRON) FOLIC ACID I.P. 1.5MG. VITAMIN B12 I.P. 15MCG. ZINC AS ZINC GLUCONATE U.S.P 7.5MG. FLAVOURED SYRUPY BASE Q.S.
Sodium feredetate feredetate which is a new generation haematinic and is a chelate form of iron. It does not dissociate in the stomach and thus there is minimal gastric disturbances whether it is Diarrohoea, Constipation, Nausea or Vomiting which is very commonly associated with any conventional iron. The relative bioavailability of sodium feredetate is 2.5 to 10 times more, therefore sodium feredetate produces faster rise in haemoglobin as compared to conventional iron and carbonyl iron. Clofiron tablet provides 231 mg of sodium feredetate equivalent to 33mg of elemental iron.
Vitamin B12 Cyanocobalamin) is a water soluble B vitamin. The mechanism of action is straightforward: the hydroxycobalamin hydroxide ligand is displaced by the toxic cyanide ion, and the resulting harmless B12 complex is excreted in urine.B12 is also known as cobalamin because it contains cobalt. B12 is only produced by bacteria. So it is only found in food products of animal origin and in some fermented vegetable products. B12 works closely with another B vitamin, Folic acid in reactions involved with DNA synthesis, blood cell formation, nervous sytem formation and heart health.
Folic acid is essential for normal erythropoiesis process by exogenous administration. Folic acid is vital for the biosynthesis of purines and thymidylate of nucleic acids. Folic acid is rapidly absorbed in the proximal portion of the small intestine. After oral administration, the Cmax can be achieved within one hour. Folic acid is well-distributed in all over the body tissues and stored in hepatic tissues. Folic acid is metabolized in liver into dihydrofolate and tetrahydrofolate forms. About 90% of the administered dose is excreted via the urine.
Zinc Zinc is an essential mineral. In children it causes growth retardation, delayed sexual maturation, infection susceptibility, and diarrhea. Zinc stimulates the activity of about 200 enzymes, maintain healthy immune system, maintains memory, prevents premature delivery, helps AIDS patients to increase immunity, has anti-inflammatory benefits , needed for DNA synthesis, helps normal growth and development, helps sperm production and ovulation, helps in digestion of food, prevents hair loss and Alopecia, provides healthy nails, strengthen bone, helps to fight infection, helps in controlling diabetes, helps acne and wound healing, is vital in protein stnthesis, helps in carrying cabon-di-oxide from the cells. Zinc requirements Infants- 0 - 6 months: 2 milligrams per day (mg/day), 7 - 12 months: 3 mg/day /, Children: 1 - 3 years: 3 mg/day, 4 - 8 years: 5 mg/day, 9 - 13 years: 8 mg/day /Adolescents and Adults - Males age 14 and over: 11 mg/day, Females age 14 to 18 years: 9 mg/day, Females age 19 and over: 8 mg/day.
Menorrhagia is an abnormally heavy and prolonged menstrual period at regular intervals. Menorrhagia can be caused by abnormal blood clotting, disruption of normal hormonal regulation of periods, or disorders of the endometrial lining of the uterus. Depending upon the cause, it may be associated with abnormally painful periods (Dysmenorrhea).
Anaemia is a decrease in number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. Because hemoglobin (found inside RBCs) normally carries oxygen from the lungs to the tissues, anemia leads to hypoxia (lack of oxygen) in organs. Anemia can be classified based on the morphology of RBCs. The three main classes include excessive blood loss (acutely such as a hemorrhage or chronically through low-volume loss), excessive blood cell destruction (hemolysis) or deficient red blood cell production (ineffective hematopoiesis).
Iron chelate, , also known as chelated iron, is a soluble complex of iron, sodium and a chelating agent such as ethylenediaminetetraacetate (EDTA), EDDHA, or others, used to make the iron soluble in water.
Carbonyl iron is a highly pure (97.5% for grade S, 99.5+% for grade R) iron, prepared by chemical decomposition of purified iron pentacarbonyl.
Hemoglobin or Hb, is the iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates as well as the tissues of some invertebrates. Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the rest of the body (i.e. the tissues). For men, 13.5 to 17.5 grams per deciliter and for women, 12.0 to 15.5 grams per deciliter is the normal Hb level.
Serum Ferritin is a universal intracellular protein that stores iron and releases it in a controlled fashion.
Once daily one tablet or 5-10 ml or as directed by the doctor.