Atorvastatin is a member of the drug class known as statins, used for lowering blood cholesterol. It also
stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms. Like all statins,
atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in
production of cholesterol in the body. As with other statins, atorvastatin is a competitive inhibitor of HMG-CoA
reductase. HMG-CoA reductase catalyzes the reduction of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) to
mevalonate, which is the rate-limiting step in hepatic cholesterol biosynthesis. Inhibition of the enzyme decreases
cholesterol synthesis, increasing expression of low-density lipoprotein receptors (LDL receptors) on hepatocytes.
This increases LDL uptake by the hepatocytes, decreasing the amount of LDL-cholesterol in the blood. Like other statins,
atorvastatin also reduces blood levels of triglycerides and slightly increases levels of HDL-cholesterol. In clinical
trials, drugs that block cholesterol uptake like ezetimibe combine with and complement those that block biosynthesis
like atorvastatin or simvastatin in lowering cholesterol or targeting levels of LDL.
Aspirin Aspirin 75mg Tablets are principally used to prevent blood clots forming following a heart attack
or stroke or to help prevent heart attacks and strokes in patients who have previously suffered from these conditions.
They may have been prescribed for you if you have recently had by-pass surgery.
Atorvastatin+Aspirin is used for prevention of heart attack and stroke. Atorvastatin + Aspirin is a combination
of two medicines: Atorvastatin and Aspirin, which prevents heart attack and stroke. Atorvastatin is a lipid-lowering
medication that blocks an enzyme required in the body to make cholesterol
INDICATIONS
Hypercholesterolemia, also called dyslipidemia, is the presence of high levels of cholesterol in the blood. It is
a form of high blood lipids and "hyperlipoproteinemia" (elevated levels of lipoproteins in the blood).
Hyperlipidemia is abnormally elevated levels of any or all lipids and/or lipoproteins in the blood. It is the most
common form of dyslipidemia (which includes any abnormal lipid levels. Hyperlipidemias are divided into primary and
secondary subtypes. Primary hyperlipidemia is usually due to genetic causes (such as a mutation in a receptor protein),
while secondary hyperlipidemia arises due to other underlying causes such as diabetes.
Atorvastatin + Aspirin Uses
Atorvastatin+Aspirin is used for prevention of heart attack and stroke.
How Atorvastatin + Aspirin works
Atorvastatin + Aspirin is a combination of two medicines: Atorvastatin and Aspirin, which
prevents heart attack and stroke. Atorvastatin is a lipid-lowering medication that blocks an enzyme required in the
body to make cholesterol. It lowers the "bad" cholesterol (LDL), triglycerides and raises the "good" cholesterol (HDL).
Aspirin is a non-steroidal anti-inflammatory drug (NSAID) with anti-platelet action. It prevents the platelets from
sticking together and decreases the formation of harmful blood clots.
Common side effects of Atorvastatin + Aspirin
Abdominal pain, Indigestion, Constipation, Flatulence, Increased liver enzymes, Hepatitis
(viral infection of liver), Reye's syndrome like symptoms
NOTE
Cholesterol is a waxy substance that provides your body with energy and is used to make hormones and bile acids
necessary to help digest food. Cholesterol is made naturally by the body but is also taken in from some foods. Your body
needs cholesterol to function properly, but having too much can cause a buildup of plaque in the arteries, which may lead
to heart disease or stroke. Cholesterol travels throughout the body in little packages called lipoproteins which are made
up of blood fats called lipids and proteins. Two main types of lipoproteins carry cholesterol are LDl & HDL.
LDL-C is known as the “bad” cholesterol because it carries cholesterol to tissues, including the arteries.” LDL
cholesterol is the amount of cholesterol fat circulating in your blood, which can be used to estimate the LDL getting into
the artery wall — the cause of plaque build-up and driving force behind atherosclerosis, heart disease and stroke.
HDL-C is known as the “good” cholesterol because it helps take “bad” cholesterol out of the body. HDL-C removes
LDL-C from your blood. The higher your HDL-C level, the more “bad” cholesterol your body can remove. Research has shown
that for every one mg/dL increase in HDL-C, your risk of a heart attack drops three to four percent. Because studies have
shown that low HDL-C may be a greater risk factor for heart disease in women, guidelines for healthy HDL-C levels differ
for men and women.
Triglycerides are another type of lipid, or fat, found both in the blood and in foods. High triglycerides are often
caused by being overweight, a lack of physical activity, cigarette smoking, excess alcohol intake, or a diet very high in
carbohydrates–the sugars and starches found in bread, cereals, fruits, etc. When triglycerides are high risk of LDL is
higher. High levels of triglycerides have been linked to increased heart disease risk–particularly in women. Research shows
that women with high triglycerides and a waist larger than 35 inches are three times more likely to die of heart disease
than those without those risk factors. People with diabetes tend to have higher triglycerides than those without the condition.
Diabetic patients also face greater risks if they have a high triglyceride count.
Total cholesterol is the sum of all cholesterol in the blood. Even if your total cholesterol is below 200 mg/dL, you
may still be at risk for heart disease if your individual lipid measures are not within recommended levels.
Digoxin is a medication used to treat various heart conditions. Most frequently it is used for atrial fibrillation,
atrial flutter, and heart failure. Digoxin is taken by mouth or by injection into a vein.
DOSE
One tablet once daily or as directed by the doctor.
INTRODUCTION
It contains atorvastatin 10 mg. & atorvastatin 10 mg + aspirine 75 mg.
Atorvastatin is a member of the drug class known as statins, used for lowering blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body. As with other statins, atorvastatin is a competitive inhibitor of HMG-CoA reductase. HMG-CoA reductase catalyzes the reduction of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) to mevalonate, which is the rate-limiting step in hepatic cholesterol biosynthesis. Inhibition of the enzyme decreases cholesterol synthesis, increasing expression of low-density lipoprotein receptors (LDL receptors) on hepatocytes. This increases LDL uptake by the hepatocytes, decreasing the amount of LDL-cholesterol in the blood. Like other statins, atorvastatin also reduces blood levels of triglycerides and slightly increases levels of HDL-cholesterol. In clinical trials, drugs that block cholesterol uptake like ezetimibe combine with and complement those that block biosynthesis like atorvastatin or simvastatin in lowering cholesterol or targeting levels of LDL.
Aspirin Aspirin 75mg Tablets are principally used to prevent blood clots forming following a heart attack or stroke or to help prevent heart attacks and strokes in patients who have previously suffered from these conditions. They may have been prescribed for you if you have recently had by-pass surgery.
Atorvastatin+Aspirin is used for prevention of heart attack and stroke. Atorvastatin + Aspirin is a combination of two medicines: Atorvastatin and Aspirin, which prevents heart attack and stroke. Atorvastatin is a lipid-lowering medication that blocks an enzyme required in the body to make cholesterol
Hypercholesterolemia, also called dyslipidemia, is the presence of high levels of cholesterol in the blood. It is a form of high blood lipids and "hyperlipoproteinemia" (elevated levels of lipoproteins in the blood).
Hyperlipidemia is abnormally elevated levels of any or all lipids and/or lipoproteins in the blood. It is the most common form of dyslipidemia (which includes any abnormal lipid levels. Hyperlipidemias are divided into primary and secondary subtypes. Primary hyperlipidemia is usually due to genetic causes (such as a mutation in a receptor protein), while secondary hyperlipidemia arises due to other underlying causes such as diabetes.
Atorvastatin + Aspirin Uses
Atorvastatin+Aspirin is used for prevention of heart attack and stroke.
How Atorvastatin + Aspirin works
Atorvastatin + Aspirin is a combination of two medicines: Atorvastatin and Aspirin, which prevents heart attack and stroke. Atorvastatin is a lipid-lowering medication that blocks an enzyme required in the body to make cholesterol. It lowers the "bad" cholesterol (LDL), triglycerides and raises the "good" cholesterol (HDL). Aspirin is a non-steroidal anti-inflammatory drug (NSAID) with anti-platelet action. It prevents the platelets from sticking together and decreases the formation of harmful blood clots.
Common side effects of Atorvastatin + Aspirin
Abdominal pain, Indigestion, Constipation, Flatulence, Increased liver enzymes, Hepatitis (viral infection of liver), Reye's syndrome like symptoms
Cholesterol is a waxy substance that provides your body with energy and is used to make hormones and bile acids necessary to help digest food. Cholesterol is made naturally by the body but is also taken in from some foods. Your body needs cholesterol to function properly, but having too much can cause a buildup of plaque in the arteries, which may lead to heart disease or stroke. Cholesterol travels throughout the body in little packages called lipoproteins which are made up of blood fats called lipids and proteins. Two main types of lipoproteins carry cholesterol are LDl & HDL.
LDL-C is known as the “bad” cholesterol because it carries cholesterol to tissues, including the arteries.” LDL cholesterol is the amount of cholesterol fat circulating in your blood, which can be used to estimate the LDL getting into the artery wall — the cause of plaque build-up and driving force behind atherosclerosis, heart disease and stroke.
HDL-C is known as the “good” cholesterol because it helps take “bad” cholesterol out of the body. HDL-C removes LDL-C from your blood. The higher your HDL-C level, the more “bad” cholesterol your body can remove. Research has shown that for every one mg/dL increase in HDL-C, your risk of a heart attack drops three to four percent. Because studies have shown that low HDL-C may be a greater risk factor for heart disease in women, guidelines for healthy HDL-C levels differ for men and women.
Triglycerides are another type of lipid, or fat, found both in the blood and in foods. High triglycerides are often caused by being overweight, a lack of physical activity, cigarette smoking, excess alcohol intake, or a diet very high in carbohydrates–the sugars and starches found in bread, cereals, fruits, etc. When triglycerides are high risk of LDL is higher. High levels of triglycerides have been linked to increased heart disease risk–particularly in women. Research shows that women with high triglycerides and a waist larger than 35 inches are three times more likely to die of heart disease than those without those risk factors. People with diabetes tend to have higher triglycerides than those without the condition. Diabetic patients also face greater risks if they have a high triglyceride count.
Total cholesterol is the sum of all cholesterol in the blood. Even if your total cholesterol is below 200 mg/dL, you may still be at risk for heart disease if your individual lipid measures are not within recommended levels.
Digoxin is a medication used to treat various heart conditions. Most frequently it is used for atrial fibrillation, atrial flutter, and heart failure. Digoxin is taken by mouth or by injection into a vein.
One tablet once daily or as directed by the doctor.